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An alternative role for FoxP3 as an effector T cell regulator controlled through CD40
The BDC2.5 T cell clone is highly diabetogenic, but the transgenic mouse generated from that clone is surprisingly slow in diabetes development. While defining pathogenic effector T cells in autoimmunity has been inconsistent, CD4(+) cells expressing the CD40 receptor (Th40 cells) are highly diabeto...
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| Main Authors: | , , , , |
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| Format: | Artigo |
| Language: | Inglês |
| Published: |
2013
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| Subjects: | |
| Online Access: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3712636/ https://ncbi.nlm.nih.gov/pubmed/23776180 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1300625 |
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