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Ligand-Promoted Alkylation of C(sp(3))–H and C(sp(2))–H Bonds

[Image: see text] 9-Methylacridine was identified as a generally effective ligand to promote a Pd(II)-catalyzed C(sp(3))–H and C(sp(2))–H alkylation of simple amides with various alkyl iodides. This alkylation reaction was applied to the preparation of unnatural amino acids and geometrically control...

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Autors principals: Zhu, Ru-Yi, He, Jian, Wang, Xiao-Chen, Yu, Jin-Quan
Format: Artigo
Idioma:Inglês
Publicat: American Chemical Society 2014
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4183600/
https://ncbi.nlm.nih.gov/pubmed/25208210
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ja508165a
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