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Ligand-Enabled Pd(II)-Catalyzed Bromination and Iodination of C(sp(3))–H Bonds

We herein report the Palladium(II)-catalyzed bromination and iodination of a variety of α-hydrogen-containing carboxylic acid and amino acid derived amides. These reactions are exclusively enabled by quinoline-type ligands. The halogenated products obtained in this reaction are highly versatile and...

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Bibliographic Details
Published in:J Am Chem Soc
Main Authors: Zhu, Ru-Yi, Saint-Denis, Tyler G., Shao, Ying, He, Jian, Sieber, Joshua D., Senanayake, Chris H., Yu, Jin-Quan
Format: Artigo
Language:Inglês
Published: 2017
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5535776/
https://ncbi.nlm.nih.gov/pubmed/28391681
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/jacs.7b02196
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