H2B Mono-ubiquitylation Facilitates Fork Stalling and Recovery during Replication Stress by Coordinating Rad53 Activation and Chromatin Assembly

The influence of mono-ubiquitylation of histone H2B (H2Bub) on transcription via nucleosome reassembly has been widely documented. Recently, it has also been shown that H2Bub promotes recovery from replication stress; however, the underling molecular mechanism remains unclear. Here, we show that H2B...

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Détails bibliographiques
Auteurs principaux: Lin, Chia-Yeh, Wu, Meng-Ying, Gay, Sophie, Marjavaara, Lisette, Lai, Mong Sing, Hsiao, Wei-Chun, Hung, Shih-Hsun, Tseng, Hsin-Yi, Wright, Duncan Edward, Wang, Chen-Yi, Hsu, Guoo-Shyng W., Devys, Didier, Chabes, Andrei, Kao, Cheng-Fu
Format: Artigo
Langue:Inglês
Publié: Public Library of Science 2014
Sujets:
Research Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4183429/
https://ncbi.nlm.nih.gov/pubmed/25275495
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pgen.1004667
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