Genome-Wide Discovery of Drug-Dependent Human Liver Regulatory Elements

Inter-individual variation in gene regulatory elements is hypothesized to play a causative role in adverse drug reactions and reduced drug activity. However, relatively little is known about the location and function of drug-dependent elements. To uncover drug-associated elements in a genome-wide ma...

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Main Authors: Smith, Robin P., Eckalbar, Walter L., Morrissey, Kari M., Luizon, Marcelo R., Hoffmann, Thomas J., Sun, Xuefeng, Jones, Stacy L., Force Aldred, Shelley, Ramamoorthy, Anuradha, Desta, Zeruesenay, Liu, Yunlong, Skaar, Todd C., Trinklein, Nathan D., Giacomini, Kathleen M., Ahituv, Nadav
格式: Artigo
語言:Inglês
出版: Public Library of Science 2014
主題:
Research Article
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC4183418/
https://ncbi.nlm.nih.gov/pubmed/25275310
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pgen.1004648
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