Genome-Wide Discovery of Drug-Dependent Human Liver Regulatory Elements

Inter-individual variation in gene regulatory elements is hypothesized to play a causative role in adverse drug reactions and reduced drug activity. However, relatively little is known about the location and function of drug-dependent elements. To uncover drug-associated elements in a genome-wide ma...

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Detalhes bibliográficos
Main Authors: Smith, Robin P., Eckalbar, Walter L., Morrissey, Kari M., Luizon, Marcelo R., Hoffmann, Thomas J., Sun, Xuefeng, Jones, Stacy L., Force Aldred, Shelley, Ramamoorthy, Anuradha, Desta, Zeruesenay, Liu, Yunlong, Skaar, Todd C., Trinklein, Nathan D., Giacomini, Kathleen M., Ahituv, Nadav
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2014
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4183418/
https://ncbi.nlm.nih.gov/pubmed/25275310
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pgen.1004648
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