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Antidepressants reduce neuroinflammatory responses and astroglial alpha-synuclein accumulation in a transgenic mouse model of Multiple System Atrophy

Multiple system atrophy (MSA) is a neurodegenerative disease characterized by the pathological accumulation of alpha-synuclein (α-syn) within oligodendroglial cells. This accumulation is accompanied by neuroinflammation with astrogliosis and microgliosis, that leads to neuronal death and subsequent...

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Bibliografiske detaljer
Main Authors: Valera, Elvira, Ubhi, Kiren, Mante, Michael, Rockenstein, Edward, Masliah, Eliezer
Format: Artigo
Sprog:Inglês
Udgivet: 2013
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4183229/
https://ncbi.nlm.nih.gov/pubmed/24310907
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/glia.22610
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