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BosR Functions as a Repressor of the ospAB Operon in Borrelia burgdorferi

The Lyme disease spirochete, Borrelia burgdorferi, must abundantly produce outer surface lipoprotein A (OspA) in the tick vector but downregulate OspA in mammals in order to evade the immune system and maintain its natural enzootic cycle. Here, we show that BosR binds two regulatory elements of the...

詳細記述

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書誌詳細
主要な著者: Shi, Yanlin, Dadhwal, Poonam, Li, Xin, Liang, Fang Ting
フォーマット: Artigo
言語:Inglês
出版事項: Public Library of Science 2014
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC4182837/
https://ncbi.nlm.nih.gov/pubmed/25271631
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0109307
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