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BosR Functions as a Repressor of the ospAB Operon in Borrelia burgdorferi
The Lyme disease spirochete, Borrelia burgdorferi, must abundantly produce outer surface lipoprotein A (OspA) in the tick vector but downregulate OspA in mammals in order to evade the immune system and maintain its natural enzootic cycle. Here, we show that BosR binds two regulatory elements of the...
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| Main Authors: | , , , |
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| Format: | Artigo |
| Language: | Inglês |
| Published: |
Public Library of Science
2014
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| Subjects: | |
| Online Access: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4182837/ https://ncbi.nlm.nih.gov/pubmed/25271631 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0109307 |
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