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BosR Functions as a Repressor of the ospAB Operon in Borrelia burgdorferi

The Lyme disease spirochete, Borrelia burgdorferi, must abundantly produce outer surface lipoprotein A (OspA) in the tick vector but downregulate OspA in mammals in order to evade the immune system and maintain its natural enzootic cycle. Here, we show that BosR binds two regulatory elements of the...

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Autores principales: Shi, Yanlin, Dadhwal, Poonam, Li, Xin, Liang, Fang Ting
Formato: Artigo
Lenguaje:Inglês
Publicado: Public Library of Science 2014
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC4182837/
https://ncbi.nlm.nih.gov/pubmed/25271631
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0109307
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