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BosR Functions as a Repressor of the ospAB Operon in Borrelia burgdorferi

The Lyme disease spirochete, Borrelia burgdorferi, must abundantly produce outer surface lipoprotein A (OspA) in the tick vector but downregulate OspA in mammals in order to evade the immune system and maintain its natural enzootic cycle. Here, we show that BosR binds two regulatory elements of the...

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Detalhes bibliográficos
Main Authors: Shi, Yanlin, Dadhwal, Poonam, Li, Xin, Liang, Fang Ting
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4182837/
https://ncbi.nlm.nih.gov/pubmed/25271631
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0109307
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