The CXXC Motifs Are Essential for the Function of BosR in Borrelia burgdorferi

BosR, a Fur family member, is essential for the pathogenesis of the Lyme disease pathogen, Borrelia burgdorferi. Unlike typical Fur proteins in which DNA binding represses gene expression, binding of BosR to the rpoS promoter directly activates rpoS transcription in B. burgdorferi. However, virtuall...

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Bibliographic Details
Published in:Front Cell Infect Microbiol
Main Authors: Mason, Charlotte, Liu, Xiaoyan, Prabhudeva, Spoorthy, Ouyang, Zhiming
Format: Artigo
Language:Inglês
Published: Frontiers Media S.A. 2019
Subjects:
Cellular and Infection Microbiology
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC6476982/
https://ncbi.nlm.nih.gov/pubmed/31041197
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fcimb.2019.00109
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