The CXXC Motifs Are Essential for the Function of BosR in Borrelia burgdorferi

BosR, a Fur family member, is essential for the pathogenesis of the Lyme disease pathogen, Borrelia burgdorferi. Unlike typical Fur proteins in which DNA binding represses gene expression, binding of BosR to the rpoS promoter directly activates rpoS transcription in B. burgdorferi. However, virtuall...

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Bibliografiska uppgifter
I publikationen:Front Cell Infect Microbiol
Huvudupphovsmän: Mason, Charlotte, Liu, Xiaoyan, Prabhudeva, Spoorthy, Ouyang, Zhiming
Materialtyp: Artigo
Språk:Inglês
Publicerad: Frontiers Media S.A. 2019
Ämnen:
Cellular and Infection Microbiology
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC6476982/
https://ncbi.nlm.nih.gov/pubmed/31041197
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fcimb.2019.00109
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