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The CXXC Motifs Are Essential for the Function of BosR in Borrelia burgdorferi

BosR, a Fur family member, is essential for the pathogenesis of the Lyme disease pathogen, Borrelia burgdorferi. Unlike typical Fur proteins in which DNA binding represses gene expression, binding of BosR to the rpoS promoter directly activates rpoS transcription in B. burgdorferi. However, virtuall...

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Detalhes bibliográficos
Publicado no:Front Cell Infect Microbiol
Main Authors: Mason, Charlotte, Liu, Xiaoyan, Prabhudeva, Spoorthy, Ouyang, Zhiming
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6476982/
https://ncbi.nlm.nih.gov/pubmed/31041197
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fcimb.2019.00109
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