Mesenchymal stem cells are efficiently transduced with adenoviruses bearing type 35-derived fibers and the transduced cells with the IL-28A gene produces cytotoxicity to lung carcinoma cells co-cultured

BACKGROUND: Transduction of human mesenchymal stem cells (MSCs) with type 5 adenoviruses (Ad5) is limited in the efficacy because of the poor expression level of the coxsackie adenovirus receptor (CAR) molecules. We examined a possible improvement of Ad-mediated gene transfer in MSCs by substituting...

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Detalhes bibliográficos
Main Authors: Suzuki, Takeo, Kawamura, Kiyoko, Li, Quanhai, Okamoto, Shinya, Tada, Yuji, Tatsumi, Koichiro, Shimada, Hideaki, Hiroshima, Kenzo, Yamaguchi, Naoto, Tagawa, Masatoshi
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2014
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4182771/
https://ncbi.nlm.nih.gov/pubmed/25255777
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2407-14-713
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