Combination of a third generation bisphosphonate and replication-competent adenoviruses augments the cytotoxicity on mesothelioma

BACKGROUND: Approximately 80 % of mesothelioma specimens have the wild-type p53 gene, whereas they contain homozygous deletions in the INK4A/ARF locus that encodes p14(ARF) and the 16(INK4A) genes. Consequently, the majority of mesothelioma is defective of the p53 pathways. We examined whether zoled...

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Detalhes bibliográficos
Publicado no:BMC Cancer
Main Authors: Jiang, Yuanyuan, Zhong, Boya, Kawamura, Kiyoko, Morinaga, Takao, Shingyoji, Masato, Sekine, Ikuo, Tada, Yuji, Tatsumi, Koichiro, Shimada, Hideaki, Hiroshima, Kenzo, Tagawa, Masatoshi
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2016
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4942884/
https://ncbi.nlm.nih.gov/pubmed/27405588
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12885-016-2483-y
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