Role of Somatostatin Receptor-2 in Gentamicin-Induced Auditory Hair Cell Loss in the Mammalian Inner Ear

Hair cells and spiral ganglion neurons of the mammalian auditory system do not regenerate, and their loss leads to irreversible hearing loss. Aminoglycosides induce auditory hair cell death in vitro, and evidence suggests that phosphatidylinositol-3-kinase/Akt signaling opposes gentamicin toxicity v...

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Sparad:
Bibliografiska uppgifter
Huvudupphovsmän: Brand, Yves, Radojevic, Vesna, Sung, Michael, Wei, Eric, Setz, Cristian, Glutz, Andrea, Leitmeyer, Katharina, Bodmer, Daniel
Materialtyp: Artigo
Språk:Inglês
Publicerad: Public Library of Science 2014
Ämnen:
Research Article
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC4182454/
https://ncbi.nlm.nih.gov/pubmed/25268135
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0108146
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