All Akt Isoforms (Akt1, Akt2, Akt3) Are Involved in Normal Hearing, but Only Akt2 and Akt3 Are Involved in Auditory Hair Cell Survival in the Mammalian Inner Ear

The kinase Akt is a key downstream mediator of the phosphoinositide-3-kinase signaling pathway and participates in a variety of cellular processes. Akt comprises three isoforms each encoded by a separate gene. There is evidence to indicate that Akt is involved in the survival and protection of audit...

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Publicado en:PLoS One
Main Authors: Brand, Yves, Levano, Soledad, Radojevic, Vesna, Naldi, Arianne Monge, Setz, Cristian, Ryan, Allen F., Pak, Kwang, Hemmings, Brian A., Bodmer, Daniel
Formato: Artigo
Idioma:Inglês
Publicado: Public Library of Science 2015
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Research Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC4374771/
https://ncbi.nlm.nih.gov/pubmed/25811375
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0121599
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