Immunotherapeutic efficacy of recombinant Mycobacterium smegmatis expressing Ag85B–ESAT6 fusion protein against persistent tuberculosis infection in mice

The application of immunotherapy in combination with chemotherapy is considered an effective treatment strategy against persistent Mycobacterium tuberculosis (Mtb) infection. In this study, we constructed a novel recombinant Mycobacterium smegmatis (rMS) strain that expresses Ag85B and ESAT6 fusion...

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Bibliografiske detaljer
Main Authors: Wang, Ping, Wang, Limei, Zhang, Wei, Bai, Yinlan, Kang, Jian, Hao, Yanfei, Luo, Tailai, Shi, Changhong, Xu, Zhikai
Format: Artigo
Sprog:Inglês
Udgivet: Landes Bioscience 2014
Fag:
Research Paper
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4181032/
https://ncbi.nlm.nih.gov/pubmed/23982126
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/hv.26171
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