Characterisation of a live Salmonella vaccine stably expressing the Mycobacterium tuberculosis Ag85B–ESAT6 fusion protein

A recombinant Salmonella enterica serovar Typhimurium (S. Typhimurium) vaccine strain was constructed that stably expressed the Mycobacterium tuberculosis fusion antigen Ag85B–ESAT6 from the chromosome. Live oral vaccination of mice with the Salmonella/Ag85B–ESAT6 strain generated a potent anti-Ag85...

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Detalhes bibliográficos
Main Authors: Hall, Lindsay J., Clare, Simon, Pickard, Derek, Clark, Simon O., Kelly, Dominic L.F., Ghany, Moataz Abd El, Hale, Christine, Dietrich, Jes, Andersen, Peter, Marsh, Philip D., Dougan, Gordon
Formato: Artigo
Idioma:Inglês
Publicado em: Elsevier Science 2009
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2789253/
https://ncbi.nlm.nih.gov/pubmed/19755145
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.vaccine.2009.09.007
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