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Candidate Live, Attenuated Salmonella enterica Serotype Typhimurium Vaccines with Reduced Fecal Shedding Are Immunogenic and Effective Oral Vaccines

Environmental shedding of genetically manipulated microorganisms is an issue impeding the development of new live vaccines. We have investigated the immunogenicity of a number of novel Salmonella enterica serotype Typhimurium oral vaccine candidates that express the fragment C (TetC) component of te...

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主要な著者: Abd El Ghany, Moataz, Jansen, Angela, Clare, Simon, Hall, Lindsay, Pickard, Derek, Kingsley, Robert A., Dougan, Gordon
フォーマット: Artigo
言語:Inglês
出版事項: American Society for Microbiology 2007
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オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC1865686/
https://ncbi.nlm.nih.gov/pubmed/17296764
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.01655-06
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