Candidate Live, Attenuated Salmonella enterica Serotype Typhimurium Vaccines with Reduced Fecal Shedding Are Immunogenic and Effective Oral Vaccines

Environmental shedding of genetically manipulated microorganisms is an issue impeding the development of new live vaccines. We have investigated the immunogenicity of a number of novel Salmonella enterica serotype Typhimurium oral vaccine candidates that express the fragment C (TetC) component of te...

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Bibliographische Detailangaben
Hauptverfasser: Abd El Ghany, Moataz, Jansen, Angela, Clare, Simon, Hall, Lindsay, Pickard, Derek, Kingsley, Robert A., Dougan, Gordon
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Microbiology 2007
Schlagworte:
Microbial Immunity and Vaccines
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1865686/
https://ncbi.nlm.nih.gov/pubmed/17296764
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.01655-06
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