Candidate Live, Attenuated Salmonella enterica Serotype Typhimurium Vaccines with Reduced Fecal Shedding Are Immunogenic and Effective Oral Vaccines

Environmental shedding of genetically manipulated microorganisms is an issue impeding the development of new live vaccines. We have investigated the immunogenicity of a number of novel Salmonella enterica serotype Typhimurium oral vaccine candidates that express the fragment C (TetC) component of te...

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Hlavní autoři: Abd El Ghany, Moataz, Jansen, Angela, Clare, Simon, Hall, Lindsay, Pickard, Derek, Kingsley, Robert A., Dougan, Gordon
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Microbiology 2007
Témata:
Microbial Immunity and Vaccines
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC1865686/
https://ncbi.nlm.nih.gov/pubmed/17296764
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.01655-06
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