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Characterisation of a live Salmonella vaccine stably expressing the Mycobacterium tuberculosis Ag85B–ESAT6 fusion protein

A recombinant Salmonella enterica serovar Typhimurium (S. Typhimurium) vaccine strain was constructed that stably expressed the Mycobacterium tuberculosis fusion antigen Ag85B–ESAT6 from the chromosome. Live oral vaccination of mice with the Salmonella/Ag85B–ESAT6 strain generated a potent anti-Ag85...

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Dettagli Bibliografici
Autori principali: Hall, Lindsay J., Clare, Simon, Pickard, Derek, Clark, Simon O., Kelly, Dominic L.F., Ghany, Moataz Abd El, Hale, Christine, Dietrich, Jes, Andersen, Peter, Marsh, Philip D., Dougan, Gordon
Natura: Artigo
Lingua:Inglês
Pubblicazione: Elsevier Science 2009
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2789253/
https://ncbi.nlm.nih.gov/pubmed/19755145
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.vaccine.2009.09.007
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