Immunotherapeutic efficacy of recombinant Mycobacterium smegmatis expressing Ag85B–ESAT6 fusion protein against persistent tuberculosis infection in mice

The application of immunotherapy in combination with chemotherapy is considered an effective treatment strategy against persistent Mycobacterium tuberculosis (Mtb) infection. In this study, we constructed a novel recombinant Mycobacterium smegmatis (rMS) strain that expresses Ag85B and ESAT6 fusion...

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Detalhes bibliográficos
Main Authors: Wang, Ping, Wang, Limei, Zhang, Wei, Bai, Yinlan, Kang, Jian, Hao, Yanfei, Luo, Tailai, Shi, Changhong, Xu, Zhikai
Formato: Artigo
Idioma:Inglês
Publicado em: Landes Bioscience 2014
Assuntos:
Research Paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4181032/
https://ncbi.nlm.nih.gov/pubmed/23982126
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/hv.26171
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