Protective and Therapeutic Efficacy of Mycobacterium smegmatis Expressing HBHA-hIL12 Fusion Protein against Mycobacterium tuberculosis in Mice

Tuberculosis (TB) remains a major worldwide health problem. The only vaccine against TB, Mycobacterium bovis Bacille Calmette-Guerin (BCG), has demonstrated relatively low efficacy and does not provide satisfactory protection against the disease. More efficient vaccines and improved therapies are ur...

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Dades bibliogràfiques
Autors principals: Zhao, Shanmin, Zhao, Yong, Mao, Fengfeng, Zhang, Caiqin, Bai, Bing, Zhang, Hai, Shi, Changhong, Xu, Zhikai
Format: Artigo
Idioma:Inglês
Publicat: Public Library of Science 2012
Matèries:
Research Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3283714/
https://ncbi.nlm.nih.gov/pubmed/22363768
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0031908
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