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Biodegradable poly(amine-co-ester) terpolymers for targeted gene delivery
Many synthetic polycationic vectors for non-viral gene delivery show high efficiency in vitro, but their usually excessive charge density makes them toxic for in vivo applications. Here we describe the synthesis of a series of high molecular weight terpolymers with low charge density, and show that...
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| Autors principals: | , , , , , , , |
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| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
2011
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4180913/ https://ncbi.nlm.nih.gov/pubmed/22138789 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nmat3187 |
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