Structure, function and inhibition of ent-kaurene synthase from Bradyrhizobium japonicum

We report the first X-ray crystal structure of ent-kaur-16-ene synthase from Bradyrhizobium japonicum, together with the results of a site-directed mutagenesis investigation into catalytic activity. The structure is very similar to that of the α domains of modern plant terpene cyclases, a result tha...

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Autores principales: Liu, Wenting, Feng, Xinxin, Zheng, Yingying, Huang, Chun-Hsiang, Nakano, Chiaki, Hoshino, Tsutomu, Bogue, Shannon, Ko, Tzu-Ping, Chen, Chun-Chi, Cui, Yunfeng, Li, Jian, Wang, Iren, Hsu, Shang-Te Danny, Oldfield, Eric, Guo, Rey-Ting
Formato: Artigo
Lenguaje:Inglês
Publicado: Nature Publishing Group 2014
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Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC4180811/
https://ncbi.nlm.nih.gov/pubmed/25269599
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep06214
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