Characterization of RNA binding and chaperoning activities of HIV-1 Vif protein: Importance of the C-terminal unstructured tail

The viral infectivity factor (Vif) is essential for the productive infection and dissemination of HIV-1 in non-permissive cells, containing the cellular anti-HIV defense cytosine deaminases APOBEC3 (A3G and A3F). Vif neutralizes the antiviral activities of the APOBEC3G/F by diverse mechanisms includ...

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Autors principals: Sleiman, Dona, Bernacchi, Serena, Xavier Guerrero, Santiago, Brachet, Franck, Larue, Valéry, Paillart, Jean-Christophe, Tisné, Carine
Format: Artigo
Idioma:Inglês
Publicat: Landes Bioscience 2014
Matèries:
Research Paper
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4179964/
https://ncbi.nlm.nih.gov/pubmed/25144404
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/rna.29546
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