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The Interaction between tRNA(Lys) (3) and the Primer Activation Signal Deciphered by NMR Spectroscopy

The initiation of reverse transcription of the human immunodeficiency virus type 1 (HIV-1) requires the opening of the three-dimensional structure of the primer tRNA(Lys) (3) for its annealing to the viral RNA at the primer binding site (PBS). Despite the fact that the result of this rearrangement i...

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Autores principales: Sleiman, Dona, Barraud, Pierre, Brachet, Franck, Tisne, Carine
Formato: Artigo
Lenguaje:Inglês
Publicado: Public Library of Science 2013
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3675109/
https://ncbi.nlm.nih.gov/pubmed/23762248
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0064700
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