HIV-1 Vif binds to APOBEC3G mRNA and inhibits its translation

The HIV-1 viral infectivity factor (Vif) allows productive infection of non-permissive cells (including most natural HIV-1 targets) by counteracting the cellular cytosine deaminases APOBEC-3G (hA3G) and hA3F. The Vif-induced degradation of these restriction factors by the proteasome has been extensi...

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Detalhes bibliográficos
Main Authors: Mercenne, Gaëlle, Bernacchi, Serena, Richer, Delphine, Bec, Guillaume, Henriet, Simon, Paillart, Jean-Christophe, Marquet, Roland
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2010
Assuntos:
RNA
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2810999/
https://ncbi.nlm.nih.gov/pubmed/19910370
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkp1009
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