Translational regulation of APOBEC3G mRNA by Vif requires its 5′UTR and contributes to restoring HIV-1 infectivity

The essential HIV-1 viral infectivity factor (Vif) allows productive infection of non-permissive cells expressing cytidine deaminases APOBEC3G (A3G) and A3F by decreasing their cellular level, and preventing their incorporation into virions. Unlike the Vif-induced degradation of A3G, the functional...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:Sci Rep
Egile Nagusiak: Guerrero, Santiago, Libre, Camille, Batisse, Julien, Mercenne, Gaëlle, Richer, Delphine, Laumond, Géraldine, Decoville, Thomas, Moog, Christiane, Marquet, Roland, Paillart, Jean-Christophe
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: Nature Publishing Group 2016
Gaiak:
Article
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC5171582/
https://ncbi.nlm.nih.gov/pubmed/27996044
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep39507
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