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Tumultuous Relationship between the Human Immunodeficiency Virus Type 1 Viral Infectivity Factor (Vif) and the Human APOBEC-3G and APOBEC-3F Restriction Factors

Summary: The viral infectivity factor (Vif) is dispensable for human immunodeficiency virus type 1 (HIV-1) replication in so-called permissive cells but is required for replication in nonpermissive cell lines and for pathogenesis. Virions produced in the absence of Vif have an aberrant morphology an...

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Detalhes bibliográficos
Main Authors: Henriet, Simon, Mercenne, Gaëlle, Bernacchi, Serena, Paillart, Jean-Christophe, Marquet, Roland
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology (ASM) 2009
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2698415/
https://ncbi.nlm.nih.gov/pubmed/19487726
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MMBR.00040-08
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