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Importance of the proline-rich multimerization domain on the oligomerization and nucleic acid binding properties of HIV-1 Vif

The HIV-1 viral infectivity factor (Vif) is required for productive infection of non-permissive cells, including most natural HIV-1 targets, where it counteracts the antiviral activities of the cellular cytosine deaminases APOBEC-3G (A3G) and A3F. Vif is a multimeric protein and the conserved prolin...

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Detalhes bibliográficos
Main Authors: Bernacchi, Serena, Mercenne, Gaëlle, Tournaire, Clémence, Marquet, Roland, Paillart, Jean-Christophe
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2011
Assuntos:
RNA
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3064812/
https://ncbi.nlm.nih.gov/pubmed/21076154
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkq979
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