SARS-CoV ORF-9b suppresses innate immunity by targeting mitochondria and the MAVS/TRAF3/TRAF6 signalosome

Coronaviruses (CoV) have recently emerged as potentially serious pathogens that can cause significant human morbidity and death. The severe acute respiratory syndrome (SARS)-CoV was identified as the etiologic agent of the 2002-3 international SARS outbreak. Yet how SARS evades innate immune respons...

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Bibliographic Details
Main Authors: Shi, Chong-Shan, Qi, Hai-Yan, Boularan, Cedric, Huang, Ning-Na, Abu-Asab, Mones, Shelhamer, James H., Kehrl, John H.
Format: Artigo
Language:Inglês
Published: 2014
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Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4179872/
https://ncbi.nlm.nih.gov/pubmed/25135833
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1303196
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