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A crucial role for β2 integrins in podosome formation, dynamics and Toll-like-receptor-signaled disassembly in dendritic cells

The dynamic properties of podosomes, their ability to degrade the underlying matrix and their modulation by Toll-like receptor (TLR) signaling in dendritic cells (DCs) suggests they have an important role in migration. Integrins are thought to participate in formation and dynamics of podosomes but t...

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Bibliografiska uppgifter
Huvudupphovsmän: Gawden-Bone, Christian, West, Michele A., Morrison, Vicky L., Edgar, Alexander J., McMillan, Sarah J., Dill, Brian D., Trost, Matthias, Prescott, Alan, Fagerholm, Susanna C., Watts, Colin
Materialtyp: Artigo
Språk:Inglês
Publicerad: The Company of Biologists 2014
Ämnen:
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC4179490/
https://ncbi.nlm.nih.gov/pubmed/25086067
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/jcs.151167
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