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Forces and constraints controlling podosome assembly and disassembly

Podosomes are a singular category of integrin-mediated adhesions important in the processes of cell migration, matrix degradation and cancer cell invasion. Despite a wealth of biochemical studies, the effects of mechanical forces on podosome integrity and dynamics are poorly understood. Here, we sho...

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Publicat a:Philos Trans R Soc Lond B Biol Sci
Autors principals: Rafiq, Nisha Bte Mohd, Grenci, Gianluca, Lim, Cheng Kai, Kozlov, Michael M., Jones, Gareth E., Viasnoff, Virgile, Bershadsky, Alexander D.
Format: Artigo
Idioma:Inglês
Publicat: The Royal Society 2019
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6627021/
https://ncbi.nlm.nih.gov/pubmed/31431172
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1098/rstb.2018.0228
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