Homeostatic Cytokines Induce CD4 Downregulation in African Green Monkeys Independently of Antigen Exposure To Generate Simian Immunodeficiency Virus-Resistant CD8αα T Cells

Eitemau Tebyg

• Cytotoxic T cell functions accumulate when CD4 is downregulated by CD4(+) T cells in African green monkeys()
  gan: Vinton, Carol L., et al.
  Cyhoeddwyd: (2017)
• Down-regulation of CD4 by memory CD4(+) T cells in vivo renders African green monkeys resistant to progressive SIVagm infection
  gan: Beaumier, Coreen M., et al.
  Cyhoeddwyd: (2009)
• CD4-Like Immunological Function by CD4(−) T Cells in Multiple Natural Hosts of Simian Immunodeficiency Virus
  gan: Vinton, Carol, et al.
  Cyhoeddwyd: (2011)
• Simian Immunodeficiency Virus SIVagm Efficiently Utilizes Non-CCR5 Entry Pathways in African Green Monkey Lymphocytes: Potential Role for GPR15 and CXCR6 as Viral Coreceptors
  gan: Riddick, Nadeene E., et al.
  Cyhoeddwyd: (2016)
• Interleukin-2 Therapy Induces CD4 Downregulation, Which Decreases Circulating CD4 T Cell Counts, in African Green Monkeys
  gan: Mudd, Joseph C., et al.
  Cyhoeddwyd: (2016)