Ectopic DNMT3L Triggers Assembly of a Repressive Complex for Retroviral Silencing in Somatic Cells

Mammalian genomes are replete with retrotransposable elements, including endogenous retroviruses. DNA methyltransferase 3-like (DNMT3L) is an epigenetic regulator expressed in prospermatogonia, growing oocytes, and embryonic stem (ES) cells. Here, we demonstrate that DNMT3L enhances the interaction...

全面介紹

Na minha lista:
書目詳細資料
Main Authors: Kao, Tzu-Hao, Liao, Hung-Fu, Wolf, Daniel, Tai, Kang-Yu, Chuang, Ching-Yu, Lee, Hsuan-Shu, Kuo, Hung-Chih, Hata, Kenichiro, Zhang, Xing, Cheng, Xiaodong, Goff, Stephen P., Ooi, Steen K. T., Bestor, Timothy H., Lin, Shau-Ping
格式: Artigo
語言:Inglês
出版: American Society for Microbiology 2014
主題:
Cellular Response to Infection
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC4178851/
https://ncbi.nlm.nih.gov/pubmed/24991018
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.01176-14
標簽: 添加標簽
沒有標簽, 成為第一個標記此記錄!

相似書籍