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NP220 mediates silencing of unintegrated retroviral DNA
The entry of foreign DNA into many mammalian cell types triggers the innate immune system, a complex set of responses directed at preventing infection by pathogens. One aspect of the response is the potent epigenetic silencing of incoming viral DNAs(1), including the extrachromosomal DNAs formed imm...
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| Published in: | Nature |
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| Main Authors: | , , , |
| Format: | Artigo |
| Language: | Inglês |
| Published: |
2018
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| Subjects: | |
| Online Access: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6349045/ https://ncbi.nlm.nih.gov/pubmed/30487602 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41586-018-0750-6 |
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