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Histones are rapidly loaded onto unintegrated retroviral DNAs soon after nuclear entry

Chromosomal structure of nuclear DNA is usually maintained by insertion of nucleosomes into preexisting chromatin, both on newly synthesized DNA at replication forks and at sites of DNA damage. But during retrovirus infection, a histone-free DNA copy of the viral genome is synthesized that must be l...

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Publicat a:Cell Host Microbe
Autors principals: Wang, Gary Z., Wang, Ying, Goff, Stephen P.
Format: Artigo
Idioma:Inglês
Publicat: 2016
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5159289/
https://ncbi.nlm.nih.gov/pubmed/27866901
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.chom.2016.10.009
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