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Unintegrated HIV-1 DNAs are loaded with core and linker histones and transcriptionally silenced
Upon delivery into the nucleus of the host cell, linear double-stranded retroviral DNAs are either integrated into the host genome to form the provirus or act as a target of the DNA damage response and become circularized. Little is known about the chromatinization status of the unintegrated retrovi...
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| Publicado no: | Proc Natl Acad Sci U S A |
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| Main Authors: | , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
National Academy of Sciences
2019
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6876238/ https://ncbi.nlm.nih.gov/pubmed/31685613 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1912638116 |
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