High-Risk Human Papillomavirus E6 Protein Promotes Reprogramming of Fanconi Anemia Patient Cells through Repression of p53 but Does Not Allow for Sustained Growth of Induced Pluripotent Stem Cells

DNA repair plays a crucial role in embryonic and somatic stem cell biology and cell reprogramming. The Fanconi anemia (FA) pathway, which promotes error-free repair of DNA double-strand breaks, is required for somatic cell reprogramming to induced pluripotent stem cells (iPSC). Thus, cells from Fanc...

Descripción completa

Guardado en:
Detalles Bibliográficos
Autores principales: Chlon, Timothy M., Hoskins, Elizabeth E., Mayhew, Christopher N., Wikenheiser-Brokamp, Kathryn A., Davies, Stella M., Mehta, Parinda, Myers, Kasiani C., Wells, James M., Wells, Susanne I.
Formato: Artigo
Lenguaje:Inglês
Publicado: American Society for Microbiology 2014
Materias:
Transformation and Oncogenesis
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC4178785/
https://ncbi.nlm.nih.gov/pubmed/25031356
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.01533-14
Etiquetas: Agregar Etiqueta
Sin Etiquetas, Sea el primero en etiquetar este registro!

Ejemplares similares