Targeting the Warburg effect with a novel glucose transporter inhibitor to overcome gemcitabine resistance in pancreatic cancer cells

Gemcitabine resistance remains a significant clinical challenge. Here, we used a novel glucose transporter (Glut) inhibitor, CG-5, as a proof-of-concept compound to investigate the therapeutic utility of targeting the Warburg effect to overcome gemcitabine resistance in pancreatic cancer. The effect...

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Detalhes bibliográficos
Main Authors: Lai, I-Lu, Chou, Chih-Chien, Lai, Po-Ting, Fang, Chun-Sheng, Shirley, Lawrence A., Yan, Ribai, Mo, Xiaokui, Bloomston, Mark, Kulp, Samuel K., Bekaii-Saab, Tanios, Chen, Ching-Shih
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2014
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Original Manuscript
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4178465/
https://ncbi.nlm.nih.gov/pubmed/24879635
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/carcin/bgu124
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