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Downregulating Hedgehog Signaling Reduces Renal Cystogenic Potential of Mouse Models
Renal cystic diseases are a leading cause of renal failure. Mutations associated with renal cystic diseases reside in genes encoding proteins that localize to primary cilia. These cystoproteins can disrupt ciliary structure or cilia-mediated signaling, although molecular mechanisms connecting cilia...
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| Main Authors: | , , , , , , , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
American Society of Nephrology
2014
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4178433/ https://ncbi.nlm.nih.gov/pubmed/24700869 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1681/ASN.2013070735 |
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