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Ttc21b is required to restrict sonic hedgehog activity in the developing mouse forebrain
Organizing centers in the developing brain provide an assortment of instructive patterning cues, including Sonic hedgehog (Shh). Here we characterize the forebrain phenotype caused by loss of Ttc21b, a gene we identified in an ENU mutagenesis screen as a novel ciliary gene required for retrograde in...
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| Main Authors: | , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2009
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2778284/ https://ncbi.nlm.nih.gov/pubmed/19732765 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ydbio.2009.08.023 |
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