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Gpr63 is a modifier of microcephaly in Ttc21b mouse mutants
The primary cilium is a signaling center critical for proper embryonic development. Previous studies have demonstrated that mice lacking Ttc21b have impaired retrograde trafficking within the cilium and multiple organogenesis phenotypes, including microcephaly. Interestingly, the severity of the mic...
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| Publicado no: | PLoS Genet |
|---|---|
| Main Authors: | , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Public Library of Science
2019
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6881074/ https://ncbi.nlm.nih.gov/pubmed/31730647 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pgen.1008467 |
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