Llwytho...

Discovery of Methyl 4′-Methyl-5-(7-nitrobenzo[c][1,2,5]oxadiazol-4-yl)-[1,1′-biphenyl]-3-carboxylate, an Improved Small-Molecule Inhibitor of c-Myc–Max Dimerization

c-Myc is a bHLH-ZIP transcription factor that is responsible for the transcription of a wide range of target genes involved in many cancer-related cellular processes, such as proliferation, differentiation, apoptosis and metabolism. Over-expression of c-Myc has been observed in, and directly contrib...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Chauhan, Jay, Wang, Huabo, Yap, Jeremy L., Sabato, Philip E., Hu, Angela, Prochownik, Edward V., Fletcher, Steven
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: 2014
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC4177309/
https://ncbi.nlm.nih.gov/pubmed/24976143
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/cmdc.201402189
Tagiau: Ychwanegu Tag
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