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Analysis of the Linker Region Joining the Adenylation and Carrier Protein Domains of the Modular Non-Ribosomal Peptide Synthetases

Non-Ribosomal Peptide Synthetases (NRPSs) are multi-modular proteins capable of producing important peptide natural products. Using an assembly-line process the amino acid substrate and peptide intermediates are passed between the active sites of different catalytic domains of the NRPS while bound c...

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Bibliografiska uppgifter
Huvudupphovsmän: Miller, Bradley R., Sundlov, Jesse A., Drake, Eric J., Makin, Thomas A., Gulick, Andrew M.
Materialtyp: Artigo
Språk:Inglês
Publicerad: 2014
Ämnen:
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC4177296/
https://ncbi.nlm.nih.gov/pubmed/24975514
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/prot.24635
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