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The Structure of PA1221, a Non-Ribosomal Peptide Synthetase containing Adenylation and Peptidyl Carrier Protein Domains

Many bacteria use large modular enzymes for the synthesis of polyketide and peptide natural products. These multidomain enzymes contain integrated carrier domains that deliver bound substrates to multiple catalytic domains, requiring coordination of these chemical steps. Non-Ribosomal Peptide Synthe...

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Detalhes bibliográficos
Main Authors: Mitchell, Carter A., Shi, Ce, Aldrich, Courtney C., Gulick, Andrew M.
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3332334/
https://ncbi.nlm.nih.gov/pubmed/22452656
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/bi300112e
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