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Structural and functional investigation of the intermolecular interaction between NRPS adenylation and carrier protein domains

Non-ribosomal peptide synthetases (NRPSs) are modular proteins that produce peptide antibiotics and siderophores. These enzymes act as catalytic assembly lines where substrates, covalently bound to integrated carrier domains, are delivered to adjacent catalytic domains. The carrier domains are initi...

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Bibliografische gegevens
Hoofdauteurs: Sundlov, Jesse A., Shi, Ce, Wilson, Daniel J., Aldrich, Courtney C., Gulick, Andrew M.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: 2012
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3292774/
https://ncbi.nlm.nih.gov/pubmed/22365602
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.chembiol.2011.11.013
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