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Structural and functional investigation of the intermolecular interaction between NRPS adenylation and carrier protein domains
Non-ribosomal peptide synthetases (NRPSs) are modular proteins that produce peptide antibiotics and siderophores. These enzymes act as catalytic assembly lines where substrates, covalently bound to integrated carrier domains, are delivered to adjacent catalytic domains. The carrier domains are initi...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2012
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3292774/ https://ncbi.nlm.nih.gov/pubmed/22365602 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.chembiol.2011.11.013 |
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