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Direct prediction of profiles of sequences compatible to a protein structure by neural networks with fragment-based local and energy-based nonlocal profiles

Locating sequences compatible to a protein structural fold is the well-known inverse protein-folding problem. While significant progress has been made, the success rate of protein design remains low. As a result, a library of designed sequences or profile of sequences is currently employed for guidi...

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Detalhes bibliográficos
Main Authors: Li, Zhixiu, Yang, Yuedong, Faraggi, Eshel, Zhan, Jian, Zhou, Yaoqi
Formato: Artigo
Idioma:Inglês
Publicado em: 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4177274/
https://ncbi.nlm.nih.gov/pubmed/24898915
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/prot.24620
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