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Energy Functions in De Novo Protein Design: Current Challenges and Future Prospects
In the past decade, a concerted effort to successfully capture specific tertiary packing interactions produced specific three-dimensional structures for many de novo designed proteins that are validated by nuclear magnetic resonance and/or X-ray crystallographic techniques. However, the success rate...
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| Main Authors: | , , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
2013
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3851009/ https://ncbi.nlm.nih.gov/pubmed/23451890 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1146/annurev-biophys-083012-130315 |
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