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Energy Functions in De Novo Protein Design: Current Challenges and Future Prospects

In the past decade, a concerted effort to successfully capture specific tertiary packing interactions produced specific three-dimensional structures for many de novo designed proteins that are validated by nuclear magnetic resonance and/or X-ray crystallographic techniques. However, the success rate...

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Detalhes bibliográficos
Main Authors: Li, Zhixiu, Yang, Yuedong, Zhan, Jian, Dai, Liang, Zhou, Yaoqi
Formato: Artigo
Idioma:Inglês
Publicado em: 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3851009/
https://ncbi.nlm.nih.gov/pubmed/23451890
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1146/annurev-biophys-083012-130315
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